Crohn’s Disease on Clinical Evidence, BMJ

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Clinical Evidence has an update on the management of Crohn’s disease. A very useful read considering the fact that it is a disease with rising number of cases. Here is a list of the recommendations which underwent changes:

  • Aminosalicylates to maintain remission: Categorization changed from likely to be ineffective/harmful to likely to ber beneficial
  • Fish Oil: Categorization unchanged to Unknown efficacy

Treatments which are listed under beneficial include:

  • Oral corticosteroids to induce remission

Treatments which are likely to be beneficial include:

  • Laparoscopic versus open ileocecal resection
  • Methotrexate
  • Infliximab to maintain remission
  • Aminosalicylates to maintain remission after surgery
  • Azathioprine/Mercaptopurine to maintain remission after surgery
  • Enteral Nutrition [I did not know this prior to reading this review update! WOW! 🙂 ]

 

 

Skeptic Oslerphile, Scientist at the Indian Council of Medical Research, National Institute of Cholera and Enteric Diseases. Interests include: Emerging Infections, Public Health, Antimicrobial Resistance, One Health and Zoonoses, Diarrheal Diseases, Medical Education, Medical History, Open Access, Healthcare Social Media and Health2.0. Opinions are my own!

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